The transcription factor Rlm1 couples the MAPK Slt2/ERK1 pathway to the IRE1-driven unfolded protein response

Abstract Unfolded protein response (UPR) is a conserved cellular strategy that enhances the protein folding capacity of cells under stress conditions. In Saccharomyces cerevisiae, the dual kinase RNase IRE1 initiates the UPR by catalyzing the cytosolic splicing of HAC1 mRNA, a process conserved in h...

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Autori principali:	Anish Chakraborty, Saswata Chakrabarty, Jagadeesh Kumar Uppala, Kimberly Ann Mayer, Anna J. Evans, Jasmine George, Chandrima Ghosh, Ritisha Dey, Franca Ohikhuare, Shama Mirza, An Phu Tran Nguyen, Nadège Gouignard, Pradeep Chaluvally-Raghavan, Madhusudan Dey
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-04-01
Serie:	Communications Biology
Accesso online:	https://doi.org/10.1038/s42003-026-10090-6
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