Circulating tumor cells from melanoma patients show phenotypic plasticity and metastatic potential in xenograft NOD.CB17 mice

Abstract Background Innovative therapies have improved the overall survival in melanoma, although a high number of patients still experience disease progression or recurrence. Ex-vivo culture of circulating tumour cells (CTCs) represents a valuable laboratory resource for in-depth characterization o...

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Principais autores:	Claudia Felici, Francesco Mannavola, Luigia Stefania Stucci, Loren Duda, Paola Cafforio, Camillo Porta, Marco Tucci
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2022-07-01
Series:	BMC Cancer
Assuntos:	Melanoma Circulating tumor cells Phenotypic plasticity Stemness Metastases; NOD.CB17 mice
Acceso en liña:	https://doi.org/10.1186/s12885-022-09829-1
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