Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy

Abstract Reactive oxygen species (ROS)-based nanodynamic therapy is emerging as a promising approach for tumor treatment, particularly in eliciting immune responses for tumor immunotherapy. Nevertheless, the complex tumor microenvironment (TME) and the constraints of current sensitizers substantiall...

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Autori principali:	Xianbin Sun, Xinyi Wang, Xudong Li, Ya Wang, Ruofei Xu, Xinyi Shen, Ding Tan, Jingjing Liao, Haijun Chen, Yu Gao, Jianping Zheng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-06-01
Serie:	Journal of Nanobiotechnology
Soggetti:	Orchestrated coordination Chemodynamic therapy Cuproptosis Immunogenic cell death Tumor microenvironment
Accesso online:	https://doi.org/10.1186/s12951-025-03486-9
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