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Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing

Attempts to minimize scarring remain among the most difficult challenges facing surgeons, despite the use of optimal wound closure techniques. Previously, we reported improved healing of dermal excisional wounds in circadian clock neuronal PAS domain 2 (Npas2)-null mice. In this study, we performed...

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Principais autores: Yoichiro Shibuya, Akishige Hokugo, Hiroko Okawa, Takeru Kondo, Daniel Khalil, Lixin Wang, Yvonne Roca, Adam Clements, Hodaka Sasaki, Ella Berry, Ichiro Nishimura, Reza Jarrahy
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2022-01-01
Serier:eLife
Fag:
wound healing
skin
clock gene
fibroblast
high‐throughput screening
Online adgang:https://elifesciences.org/articles/71074
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