Acute EPA-induced learning and memory impairment in mice is prevented by DHA
Acute administration of EPA impairs learning and memory and hippocampal LTP in mice that was mediated through enhancing GABAergic transmission via the 5-HT6R. DHA can prevent EPA-induced impairments at a ratio of EPA to DHA similar to that in marine fish oil via the 5-HT2CR.
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| Principais autores: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2020-10-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-020-19255-1 |
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