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GPCRs overexpression and impaired fMLP-induced functions in neutrophils from chronic kidney disease patients

IntroductionG-protein coupled receptors (GPCRs) expressed on neutrophils regulate their mobilization from the bone marrow into the blood, their half-live in the circulation, and their pro- and anti-inflammatory activities during inflammation. Chronic kidney disease (CKD) is associated with systemic...

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Hoofdauteurs: Pablo Scharf, Silvana Sandri, Felipe Rizzetto, Luana Filippi Xavier, Daniela Grosso, Rebeca D. Correia-Silva, Pedro S. Farsky, Cristiane D. Gil, Sandra Helena Poliselli Farsky
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-08-01
Reeks:Frontiers in Immunology
Onderwerpen:
neutrophil-to-lymphocyte ratio
CXCR4
FPR
Annexin A1
fMLP
Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1387566/full
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