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Assessing allocation bias in stratified clinical trials with multi-component endpoints evaluated using the stratified Wei-Lachin test.

<h4>Background</h4>A common issue in rare disease stratified clinical trials with multi-component endpoints is allocation bias, as they frequently lack blinding. Allocation bias arises when future treatment allocations can be predicted from prior ones, potentially leading to patients with specific c...

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Bibliografische gegevens
Hoofdauteurs: Stefanie Schoenen, Nicole Heussen, Ralf-Dieter Hilgers
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2026-01-01
Reeks:PLoS ONE
Online toegang:https://doi.org/10.1371/journal.pone.0341039
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