Local Inflammation Precedes Diaphragm Wasting and Fibrotic Remodelling in a Mouse Model of Pancreatic Cancer

ABSTRACT Background Cancer cachexia represents a debilitating muscle wasting condition that is highly prevalent in gastrointestinal cancers, including pancreatic ductal adenocarcinoma (PDAC). Cachexia is estimated to contribute to ~30% of cancer‐related deaths, with deterioration of respiratory musc...

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Detalhes bibliográficos

Principais autores:	Daria Neyroud, Andrew C. D'Lugos, Enrique J. Trevino, Chandler S. Callaway, Jacqueline Lamm, Orlando Laitano, Brittney Poole, Michael R. Deyhle, Justina Brantley, Lam Le, Andrew R. Judge, Sarah M. Judge
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-02-01
coleção:	Journal of Cachexia, Sarcopenia and Muscle
Assuntos:	cancer cachexia inflammatory response muscle atrophy muscle fibrosis pancreatic cancer
Acesso em linha:	https://doi.org/10.1002/jcsm.13668
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