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PHRF1 promotes the class switch recombination of IgA in CH12F3-2A cells.

PHRF1 is an E3 ligase that promotes TGF-β signaling by ubiquitinating a homeodomain repressor TG-interacting factor (TGIF). The suppression of PHRF1 activity by PML-RARα facilitates the progression of acute promyelocytic leukemia (APL). PHRF1 also contributes to non-homologous end-joining in respons...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jin-Yu Lee, Nai-Lin Chou, Ya-Ru Yu, Hsin-An Shih, Hung-Wei Lin, Chine-Kuo Lee, Mau-Sun Chang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2023-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285159&type=printable
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