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Annexin A5 reduces early plaque formation in ApoE -/- mice.

Annexin A5 (AnxA5) exerts anti-inflammatory, anticoagulant and anti-apoptotic effects through its binding to cell surface expressed phosphatidylserine. We previously showed that AnxA5 can stabilize advanced atherosclerotic plaques by reducing macrophage infiltration. We now investigated the effects...

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Autores principales: Robert Stöhr, Leon Schurgers, Rick van Gorp, Armand Jaminon, Nikolaus Marx, Chris Reutelingsperger
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC5739472?pdf=render
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