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TMEM184A promotes progression and drug resistance in colorectal cancer: a bioinformatics and clinical study

Abstract The cellular origin and molecular mechanisms underlying therapeutic resistance in colorectal cancer remain largely unclear.This study integrates single-cell transcriptomics, spatial transcriptomics, molecular docking, and multi-cohort public databases to systematically elucidate the epithel...

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Furkejuvvon:
Váldodahkkit: Xueliang Bai, Zhongyuan Bai, Peng Bu, Ruijiang Liu, Guohai Zhao, Wei Cui, Yongping Cui, Yanfeng Xi
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2026-04-01
Ráidu:Scientific Reports
Fáttát:
Colorectal cancer
TMEM184A
Drug resistance
Clinical Significance
Liŋkkat:https://doi.org/10.1038/s41598-026-46674-9
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