Serum CHI3L1 levels correlate with disease activity in rheumatoid arthritis and reveal potential molecular mechanisms

ObjectiveThis study aims to elucidate the molecular regulatory mechanisms of Chitinase-3-like protein 1 (CHI3L1) in rheumatoid arthritis (RA) and its association with disease activity, focusing on its translational potential in RA diagnosis, dynamic monitoring, and precision therapy.MethodsTranscrip...

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Autors principals:	Yi Deng, Dan Wang, Chao Wang, Kaiyun Guo, Ming Lei, Yanzhao Huang, Langui Tang, Ya Ding, Yan Gao
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2025-12-01
Col·lecció:	Frontiers in Immunology
Matèries:	CHI3L1 immune infiltration molecular docking rheumatoid arthritis single-cell RNA sequencing WGCNA
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1729989/full
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