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The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion.

Arenavirus entry into host cells occurs through a low pH-dependent fusion with late endosomes that is mediated by the viral glycoprotein complex (GPC). The mechanisms of GPC-mediated membrane fusion and of virus targeting to late endosomes are not well understood. To gain insights into arenavirus fu...

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Detalhes bibliográficos
Principais autores: Ruben M Markosyan, Mariana Marin, You Zhang, Fredric S Cohen, Gregory B Melikyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2021-09-01
coleção:PLoS Pathogens
Acesso em linha:https://doi.org/10.1371/journal.ppat.1009488
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