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Single-cell transcriptomic profiling of zebrafish primary motor neurons reveals subtype-specific gene expression signatures

Summary: Motor neurons (MNs) connect the central nervous system to skeletal muscles, enabling movement. In zebrafish, the three MN subtypes, RoP, MiP, and CaP, are defined anatomically, but their molecular identities remain underexplored. Using single-cell transcriptomics of developing Tg(mnx1:gfp)...

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Main Authors: Laurie Nemoz-Billet, Nathan Gil, Chloé Exbrayat-Héritier, Mathilde Bouchet, Marilyne Malbouyres, Sandrine Hughes, Benjamin Gillet, Jonathan Enriquez, Sandrine Bretaud, Florence Ruggiero
Format: Artigo
Language:Inglês
Published: Elsevier 2025-12-01
Series:iScience
Subjects:
molecular neuroscience
developmental neuroscience
transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225024290
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