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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

The constant mutation of SARS-CoV-2 has led to the emergence of new variants, which call for urgent effective therapeutic interventions. The trimeric spike (S) protein of SARS-CoV-2 is highly immunogenic with the receptor-binding domain (RBD) that binds first to the cellular receptor angiotensin-con...

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Autori principali: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-01-01
Serie:Viruses
Soggetti:
SARS-CoV-2 variants
spike RBD
neutralizing epitope
escape mutant
cross-neutralizing antibody
Accesso online:https://www.mdpi.com/1999-4915/14/2/230
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