Eplerenone, a mineralocorticoid receptor inhibitor, reduces cirrhosis associated changes of hepatocyte glucose and lipid metabolism

Abstract Background Recent studies suggest a contribution of intrahepatic mineralocorticoid receptor (MR) activation to the development of cirrhosis. As MR blockade abrogates the development of cirrhosis and hypoxia, common during the development of cirrhosis, can activate MR in hepatocytes. But, th...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	Mohammad Mohabbulla Mohib, Sindy Rabe, Alexander Nolze, Michael Rooney, Quratul Ain, Alexander Zipprich, Michael Gekle, Barbara Schreier
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2024-12-01
Saila:	Cell Communication and Signaling
Gaiak:	Cirrhosis Mineralocorticoid receptor Hypoxia Metabolism
Sarrera elektronikoa:	https://doi.org/10.1186/s12964-024-01991-2
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!