Small CD63 + CD81+ extracellular vesicles induce autophagy via the FOXO3a pathway in pancreatic cancer cells during starvation

Abstract Pancreatic ductal adenocarcinoma (PDAC), the most common histological subtype of pancreatic cancer, is an aggressive malignancy expected to become the second leading cause of cancer-related deaths by 2040. A hallmark of PDACs is the highly desmoplastic and hypovascularized nature of its mic...

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Autori principali:	Daniel Grasso, Maximiliano A. Diaz, Laura Sobrado, Valentín Yzetta, Marcela A. Cucher, Maria L. Cerutti, Daniela L. Papademetrio, Elida Alvarez, Maria Noé Garcia
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-05-01
Serie:	Scientific Reports
Soggetti:	Pancreatic cancer Extracellular vesicles Autophagy
Accesso online:	https://doi.org/10.1038/s41598-026-52731-0
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