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Characteristics predicting the efficacy of SGLT-2 inhibitors versus GLP-1 receptor agonists on major adverse cardiovascular events in type 2 diabetes mellitus: a meta-analysis study

Abstract Background Recent large clinical trials have demonstrated cardiovascular benefits of similar overall magnitude for sodium–glucose cotransporter-2 inhibitor (SGLT-2i) and glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy in subjects with type 2 diabetes. We sought to identify subgro...

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Main Authors: Minji Sohn, Johannes W. Dietrich, Michael A. Nauck, Soo Lim
Format: Artigo
Language:Inglês
Published: BMC 2023-06-01
Series:Cardiovascular Diabetology
Subjects:
Sodium–glucose cotransporter-2 inhibitor
Glucagon-like peptide 1 receptor agonist
Major adverse cardiovascular events
Meta-regression
Meta-analysis
Diabetes mellitus, type 2
Online Access:https://doi.org/10.1186/s12933-023-01877-6
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