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Quantitative proteomic analysis of aqueous humor from patients with drusen and reticular pseudodrusen in age-related macular degeneration

Abstract Background To identify novel biomarkers related to the pathogenesis of dry age-related macular degeneration (AMD), we adopted a human retinal pigment epithelial (RPE) cell culture model that mimics some features of dry AMD including the accumulation of intra- and sub-RPE deposits. Then, we...

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Main Authors: Je-Hyun Baek, Daehan Lim, Kyu Hyung Park, Jae-Byoung Chae, Hyoik Jang, Jonghyun Lee, Hyewon Chung
Format: Artigo
Language:Inglês
Published: BMC 2018-11-01
Series:BMC Ophthalmology
Subjects:
Age-related macular degeneration
Complement
Drusen
Reticular pseudodrusen
SWATH-MS
Online Access:http://link.springer.com/article/10.1186/s12886-018-0941-9
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