Prophylactic Activation of Shh Signaling Attenuates TBI-Induced Seizures in Zebrafish by Modulating Glutamate Excitotoxicity through Eaat2a

Approximately 2 million individuals experience a traumatic brain injury (TBI) every year in the United States. Secondary injury begins within minutes after TBI, with alterations in cellular function and chemical signaling that contribute to excitotoxicity. Post-traumatic seizures (PTS) are experienc...

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Bibliografski detalji

Glavni autori:	James Hentig, Leah J. Campbell, Kaylee Cloghessy, Mijoon Lee, William Boggess, David R. Hyde
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-12-01
Serija:	Biomedicines
Teme:	traumatic brain injury blunt-force TBI post-traumatic seizures zebrafish sonic hedgehog signaling purmorphamine
Online pristup:	https://www.mdpi.com/2227-9059/10/1/32
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