New (Iso)quinolinyl-pyridine-2,6-dicarboxamide G-Quadruplex Stabilizers. A Structure-Activity Relationship Study

G-quadruplex (G4)-interactive small molecules have a wide range of potential applications, not only as drugs, but also as sensors of quadruplex structures. The purpose of this work is the synthesis of analogues of the bis-methylquinolinium-pyridine-2,6-dicarboxamide G4 ligand 360A, to identify relev...

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Bibliografiska uppgifter

Huvudupphov:	Enrico Cadoni, Pedro R. Magalhães, Rita M. Emídio, Eduarda Mendes, Jorge Vítor, Josué Carvalho, Carla Cruz, Bruno L. Victor, Alexandra Paulo
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2021-07-01
Serie:	Pharmaceuticals
Ämnen:	quinoline isoquinoline G-quadruplex ligands <i>k-RAS</i> <i>c-MYC</i> telomere
Länkar:	https://www.mdpi.com/1424-8247/14/7/669
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