Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.

The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is largely unknown. We investigated whether PPARG is epigenetically regulated in colorectal cancer (CRC) progression. PPARG expression was asses...

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Autori principali:	Massimo Pancione, Lina Sabatino, Alessandra Fucci, Vincenzo Carafa, Angela Nebbioso, Nicola Forte, Antonio Febbraro, Domenico Parente, Concetta Ambrosino, Nicola Normanno, Lucia Altucci, Vittorio Colantuoni
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2010-12-01
Serie:	PLoS ONE
Accesso online:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21151932/?tool=EBI
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