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Vitamin D receptor (VDR) contributes to the development of hypercalciuria by sensitizing VDR target genes to vitamin D in a genetic hypercalciuric stone-forming (GHS) rat model

Human idiopathic hypercalciuria (IH) is the most common cause of calcium oxalate nephrolithiasis with perturbed calcium metabolism with increased bone resorption and decreased renal calcium reabsorption, which can be phenotype-copied in the genetic hypercalciuric stone-forming (GHS) rat model. We pr...

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Principais autores: Shang Guo, Weekai Chia, Hongwei Wang, David A. Bushinsky, Biao Zhong, Murray J. Favus
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2022-05-01
coleção:Genes and Diseases
Assuntos:
Acetylation
ChIP
GHS
Methylation
Snail
VDR
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352304220301197
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