Development and Optimization of Oligonucleotide Ligation Assay (OLA) Probes for Detection of HIV-1 Resistance to Dolutegravir

The WHO currently recommends dolutegravir (DTG)-based ART for persons living with HIV infection in resource-limited-settings (RLS). To expand access to testing for HIV drug resistance (DR) to DTG in RLS, we developed probes for use in the oligonucleotide ligation assay (OLA)-Simple, a near-point of...

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Autori principali:	Ingrid A. Beck, Ceejay L. Boyce, Marley D. Bishop, Yen L. Vu, Amanda Fung, Sheila Styrchak, Nuttada Panpradist, Barry R. Lutz, Lisa M. Frenkel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-07-01
Serie:	Viruses
Soggetti:	HIV-1 integrase dolutegravir INSTI resistance drug resistance mutations drug resistance testing oligonucleotide ligation assay
Accesso online:	https://www.mdpi.com/1999-4915/16/7/1162
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