The Androgen Hormone-Induced Increase in Androgen Receptor Protein Expression Is Caused by the Autoinduction of the Androgen Receptor Translational Activity

The androgen receptor (AR) plays a central role in prostate, muscle, bone and adipose tissue. Moreover, dysregulated AR activity is a driving force in prostate cancer (PCa) initiation and progression. Consequently, antagonizing AR signalling cascades via antiandrogenic therapy is a crucial treatment...

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Autors principals:	Tiziana Siciliano, Ulrich Sommer, Alicia-Marie K. Beier, Matthias B. Stope, Angelika Borkowetz, Christian Thomas, Holger H. H. Erb
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-01-01
Col·lecció:	Current Issues in Molecular Biology
Matèries:	testosterone biphasic effect of androgens protein stability
Accés en línia:	https://www.mdpi.com/1467-3045/44/2/41
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