Restoration of proximal tubule flow–activated transport prevents cyst growth in polycystic kidney disease

Flow-activated Na+ and HCO3– transport in kidney proximal tubules (PT) underlies relatively constant fractional reabsorption during changes in glomerular filtration rate (GFR) or glomerulotubular balance (GTB). In view of hypothesized connections of epithelial cilia to flow sensing, we examined flow...

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מידע ביבליוגרפי

Principais autores:	Zhaopeng Du, Xin Tian, Ming Ma, Stefan Somlo, Alan M. Weinstein, Tong Wang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Clinical investigation 2021-05-01
סדרה:	JCI Insight
נושאים:	Nephrology
גישה מקוונת:	https://doi.org/10.1172/jci.insight.146041
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