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HER2-CD3-Fc Bispecific Antibody-Encoding mRNA Delivered by Lipid Nanoparticles Suppresses HER2-Positive Tumor Growth

The human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase receptor and tumor-associated antigen abnormally expressed in various types of cancer, including breast, ovarian, and gastric cancer. HER2 overexpression is highly correlated with increased tumor aggressiveness, p...

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Autori principali: Liang Hu, Shiming Zhang, John Sienkiewicz, Hua Zhou, Robert Berahovich, Jinying Sun, Michael Li, Adrian Ocampo, Xianghong Liu, Yanwei Huang, Hizkia Harto, Shirley Xu, Vita Golubovskaya, Lijun Wu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-07-01
Serie:Vaccines
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Accesso online:https://www.mdpi.com/2076-393X/12/7/808
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