Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage

Summary: Broadly neutralizing antibodies (bNAbs) targeting the apex of the HIV-1-envelope (Env) trimer comprise the most potent category of HIV-1 bNAbs and have emerged as promising therapeutics. Here, we investigate the development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage and rep...

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Asıl Yazarlar:	Rosemarie D. Mason, Baoshan Zhang, Nicholas C. Morano, Chen-Hsiang Shen, Krisha McKee, Ashley Heimann, Renguang Du, Alexandra F. Nazzari, Shelby Hodges, Tapan Kanai, Bob C. Lin, Mark K. Louder, Nicole A. Doria-Rose, Tongqing Zhou, Lawrence Shapiro, Mario Roederer, Peter D. Kwong, Jason Gorman
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2025-01-01
Seri Bilgileri:	Cell Reports
Konular:	CP: Immunology
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S2211124724015742
Etiketler:	Etiketle Etiket eklenmemiş, İlk siz ekleyin!

Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage

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