Disruptions of <i>rpiAB</i> Genes Encoding Ribose-5-Phosphate Isomerases in <i>E. coli</i> Increases Sensitivity of Bacteria to Antibiotics

In <i>Escherichia coli</i> cells, the main enzymes involved in pentose interconversion are ribose-5-phosphate isomerases RpiA and RpiB and ribulose-5-phosphate epimerase Rpe. The inactivation of <i>rpiAB</i> limits ribose-5-phosphate (R5P) synthesis via the oxidative branch of the pentose phosphate...

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Hauptverfasser:	Tatyana A. Seregina, Rustem S. Shakulov, Svetlana A. Sklyarova, Alexander S. Mironov
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-11-01
Schriftenreihe:	Cells
Schlagworte:	pentose phosphate pathway ribose-5-phosphate isomerases RpiA and RpiB ribose-5-phosphate antibiotics <i>Escherichia coli</i>
Online-Zugang:	https://www.mdpi.com/2073-4409/13/22/1915
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