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Deciphering the preference and predicting the viability of circular permutations in proteins.

Circular permutation (CP) refers to situations in which the termini of a protein are relocated to other positions in the structure. CP occurs naturally and has been artificially created to study protein function, stability and folding. Recently CP is increasingly applied to engineer enzyme structure...

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Библиографические подробности
Главные авторы: Wei-Cheng Lo, Tian Dai, Yen-Yi Liu, Li-Fen Wang, Jenn-Kang Hwang, Ping-Chiang Lyu
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3281007?pdf=render
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