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A clathrin mediated endocytosis scaffolding protein, Intersectin 1, changes in an isoform, brain region, and sex specific manner in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia and is characterized by the accumulation of amyloid-beta (Aβ) plaques and neurofibrillary Tau tangles in the brain. We previously identified a set of candidate AD microRNAs (miRNAs) in human cerebrospinal fluid (CSF) and used a target pred...

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Hauptverfasser: Sierra Jaye, Ursula S. Sandau, Trevor J. McFarland, Randy L. Woltjer, Julie A. Saugstad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-06-01
Schriftenreihe:Frontiers in Neuroscience
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fnins.2024.1426180/full
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