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Research progress of phosphodiesterase 5 in heart failure

Phosphodiesterase 5 (PDE5), a cyclic guanosine monophosphate (cGMP)-specific hydrolase, is targets cGMP produced by soluble guanosine cyclase (sGC) that is activated by nitric oxide (NO). It catalyzes the hydrolysis of the phosphodiester bond in cGMP and converts cGMP to the inactive 5′-GMP form. Th...

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Bibliografische gegevens
Hoofdauteur: YANG Yang, ZHANG Yarong, YANG Hongqin, WANG Jing, ZHAO Hongmei
Formaat: Artigo
Taal:Chinês
Gepubliceerd in: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-05-01
Reeks:Jichu yixue yu linchuang
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Online toegang:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-5-724.pdf
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