Effect of <i>GSTA1</i> Variants on Busulfan-Based Conditioning Regimen Prior to Allogenic Hematopoietic Stem-Cell Transplantation in Pediatric Asians

Busulfan is widely used as a chemotherapy treatment before hematopoietic stem-cell transplantation (HSCT). However, the response of busulfan is highly variable and unpredictable, whereby the pharmacogenetic interference of glutathione <i>S</i>-transferase (GST) has strong evidence in Caucasians and...

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Principais autores:	Ai-Hoc Nguyen, Mohitosh Biswas, Apichaya Puangpetch, Santirhat Prommas, Samart Pakakasama, Usanarat Anurathapan, Jiratha Rachanakul, Rattanaporn Sukprasong, Nutthan Nuntharadtanaphong, Nutcha Jongjitsook, Suradej Hongeng, Chonlaphat Sukasem
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-02-01
Series:	Pharmaceutics
Assuntos:	busulfan hematopoietic stem-cell transplantation pharmacokinetics GST genetic polymorphisms pediatric Asians
Acceso en liña:	https://www.mdpi.com/1999-4923/14/2/401
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