RBM5 is a male germ cell splicing factor and is required for spermatid differentiation and male fertility.

Alternative splicing of precursor messenger RNA (pre-mRNA) is common in mammalian cells and enables the production of multiple gene products from a single gene, thus increasing transcriptome and proteome diversity. Disturbance of splicing regulation is associated with many human diseases; however, k...

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Hlavní autoři:	Moira K O'Bryan, Brett J Clark, Eileen A McLaughlin, Rebecca J D'Sylva, Liza O'Donnell, Jacqueline A Wilce, Jessie Sutherland, Anne E O'Connor, Belinda Whittle, Christopher C Goodnow, Christopher J Ormandy, Duangporn Jamsai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS Genetics
On-line přístup:	http://europepmc.org/articles/PMC3723494?pdf=render
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