Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1

Abstract Formyl peptide receptor 1 (FPR1) mediates bacterial and mitochondrial N-formyl peptides-induced neutrophil activation. Therefore, FPR1 is an important therapeutic target for drugs to treat septic or sterile inflammatory diseases. Honokiol, a major bioactive compound of Magnoliaceae plants,...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Fu-Chao Liu, Huang-Ping Yu, Yu-Ting Syu, Jia-You Fang, Chwan-Fwu Lin, Shih-Hsin Chang, Yen-Tung Lee, Tsong-Long Hwang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Nature Portfolio 2017-07-01
श्रृंखला:	Scientific Reports
ऑनलाइन पहुंच:	https://doi.org/10.1038/s41598-017-07131-w
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