Analysis of substrate specificity and kinetics of cyclic nucleotide phosphodiesterases with N'-methylanthraniloyl-substituted purine and pyrimidine 3',5'-cyclic nucleotides by fluorescence spectrometry.

As second messengers, the cyclic purine nucleotides adenosine 3',5'-cyclic monophosphate (cAMP) and guanosine 3',5'-cyclic monophosphate (cGMP) play an essential role in intracellular signaling. Recent data suggest that the cyclic pyrimidine nucleotides cytidine 3',5'-cyclic monophosphate (cCMP) and...

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Detalles Bibliográficos

Principais autores:	Daniel Reinecke, Frank Schwede, Hans-Gottfried Genieser, Roland Seifert
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2013-01-01
Series:	PLoS ONE
Acceso en liña:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23342095/?tool=EBI
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