Integrative gene co-expression network analysis reveals protein-coding and LncRNA genes associated with Alzheimer’s disease pathology

Abstract Alzheimer’s disease (AD) is a complex neurodegenerative disorder marked by widespread molecular changes, many of which remain poorly understood. While AD pathology progresses through specific brain regions, it is unclear whether these regions are affected similarly. Long non-coding RNAs (ln...

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Detalhes bibliográficos

Principais autores:	Fatemeh Zebardast, Michael Peter Sascha Riethmüller, Katja Nowick
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-12-01
coleção:	Scientific Reports
Assuntos:	Alzheimer’s disease Consensus gene co-expression network Weighted topological overlap (wTO) Long non-coding RNAs (lncRNA) Random walk with restart (RWR)
Acesso em linha:	https://doi.org/10.1038/s41598-025-30392-9
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