Liver Transcriptome Dynamics During Hibernation Are Shaped by a Shifting Balance Between Transcription and RNA Stability

Hibernators dramatically lower metabolism to save energy while fasting for months. Prolonged fasting challenges metabolic homeostasis, yet small-bodied hibernators emerge each spring ready to resume all aspects of active life, including immediate reproduction. The liver is the body’s metabolic hub,...

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書誌詳細

主要な著者:	Austin E. Gillen, Rui Fu, Kent A. Riemondy, Jennifer Jager, Bin Fang, Mitchell A. Lazar, Sandra L. Martin
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2021-05-01
シリーズ:	Frontiers in Physiology
主題:	A-to-I RNA editing ARE-binding proteins alternative splicing hepatocyte Ictidomys tridecemlineatus
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fphys.2021.662132/full
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