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Discovery of Retro-1 Analogs Exhibiting Enhanced Anti-vaccinia Virus Activity

Orthopoxviruses (OPXVs) are an increasing threat to human health due to the growing population of OPXV-naive individuals after the discontinuation of routine smallpox vaccination. Antiviral drugs that are effective as postexposure treatments against variola virus (the causative agent of smallpox) or...

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Principais autores: Lalita Priyamvada, Philip Alabi, Andres Leon, Amrita Kumar, Suryaprakash Sambhara, Victoria A. Olson, Jason K. Sello, Panayampalli S. Satheshkumar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-04-01
Serier:Frontiers in Microbiology
Fag:
viral inhibitor
poxvirus
antiviral agent
retrograde transport
vaccinia virus
Retro-1
Online adgang:https://www.frontiersin.org/article/10.3389/fmicb.2020.00603/full
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