Pharmacokinetics of Monoclonal Antibodies in Pediatrics: Model-Based Investigation on Allometric Scaling Exponents

<b>Methods</b>: This study explored key study design factors that could impact the precision of pediatric pharmacokinetics (PK) estimation. A virtual pediatric population was constructed, incorporating diverse body weight distribution sourced from the U.S. Centers for Disease Control and Prevention...

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Detalhes bibliográficos

Principais autores:	Elvis K. Danso, Yuan Xiong, Mahesh N. Samtani, Zhenhua Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-05-01
coleção:	Pharmaceutics
Assuntos:	allometric scaling pediatric monoclonal antibodies simulation modeling study design
Acesso em linha:	https://www.mdpi.com/1999-4923/18/5/579
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