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TNF-overexpression in Borna disease virus-infected mouse brains triggers inflammatory reaction and epileptic seizures.

Proinflammatory state of the brain increases the risk for seizure development. Neonatal Borna disease virus (BDV)-infection of mice with neuronal overexpression of tumor necrosis factor-α (TNF) was used to investigate the complex relationship between enhanced cytokine levels, neurotropic virus infec...

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Bibliografiske detaljer
Principais autores: Katharina Kramer, Dirk Schaudien, Ulrich L M Eisel, Sibylle Herzog, Jürgen A Richt, Wolfgang Baumgärtner, Christiane Herden
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3405098?pdf=render
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