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Proteomic profiling of spontaneous myopia in guinea pigs

PurposeThere is a subset of guinea pigs born with spontaneous myopia that exhibit fundus characteristics similar to those of high myopia. This study aimed to further identify the traits, including proteomic profiling of the retina and plasma, in this strain of guinea pigs.MethodsSpontaneously myopic...

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Principais autores: Hong Liu, Yongli Zhou, Xiaoning Li, Huixin Sun, Yuwen Hsiao, Longbo Wen, Qinglin Xu, Zhao Chen, Weizhong Lan, Zhikuan Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-03-01
coleção:Frontiers in Medicine
Assuntos:
complement cascades
experimental myopia
ferroptosis
guinea pig
high myopia
proteomics
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2026.1757831/full
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