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Exploring the effects of naringin on oxidative stress-impaired osteogenic differentiation via the Wnt/β-catenin and PI3K/Akt pathways

Abstract This study aimed to explore naringin’s potential to promote the osteogenic differentiation of MC3T3-E1 under oxidative stress. It delved into Nar’s connection with the Wnt/β-catenin and PI3K/Akt signaling pathways. Initially, 2911 OP-related genes were analyzed, revealing close ties with th...

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Principais autores: Hui Wang, Jun Liang, Yiran Wang, Junyuan Zheng, Ying Liu, Yiyang Zhao, Yixuan Ma, Pei Chen, Xufang Yang
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2024-06-01
סדרה:Scientific Reports
נושאים:
Osteoporosis
Naringin
Oxidative stress
Wnt/β-catenin signaling pathway
PI3K/Akt signaling pathway
גישה מקוונת:https://doi.org/10.1038/s41598-024-64952-2
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