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Synergistic effect of the rifaximin–berberine combination against Klebsiella pneumoniae: RfaH targeting supported by MD simulation

The escalating crisis of antimicrobial resistance (AMR) among Gram-negative pathogens, particularly Klebsiella pneumoniae (KP), necessitates innovative strategies to enhance the efficacy of existing antibiotics. Synergistic drug combinations present a promising approach to improve therapeutic outco...

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Автори: Anam Ashraf, Mohammad Ali Khan, Arunabh Choudhury, Swati Kumari, Bader S. Alotaibi, Saba Noor, Mohd Adnan, Md. Imtaiyaz Hassan
Формат: Artigo
Мова:Inglês
Опубліковано: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2026-01-01
Серія:Biomolecules & Biomedicine
Предмети:
Synergistic effect
rifaximin-berberine
anti-termination protein RFAH
MD simulation
antibiotic resistance
K. pnuemoniae
Онлайн доступ:https://www.bjbms.org/ojs/index.php/bjbms/article/view/13776
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