Omega-3 fatty acids abrogates oxido-inflammatory and mitochondrial dysfunction-associated apoptotic responses in testis of tamoxifen-treated rats

BackgroundTamoxifen (TAM) is a widely used drug in patients with gynecomastia and breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately, TAM has been reported to exert gonadotoxic effects on male testes. Therefore, this study was designed to explore the po...

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Bibliografische Detailangaben

Hauptverfasser:	Adeyemi Fatai Odetayo, Roland Eghoghosoa Akhigbe, Moses Agbomhere Hamed, Morufu Eyitayo Balogun, David Tolulope Oluwole, Luqman Aribidesi Olayaki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-08-01
Schriftenreihe:	Frontiers in Nutrition
Schlagworte:	anticancer drugs nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-kappa B (NF-κB) signaling selective estrogen receptor modulators testicular function cytochrome c
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fnut.2024.1443895/full
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