Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models

Abstract The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 promotes epithelial-to-mesenchymal transiti...

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Egile Nagusiak:	Mario Sechi, Rahul K. Lall, Saheed O Afolabi, Anant Singh, Dinesh C. Joshi, Shing-Yan Chiu, Hasan Mukhtar, Deeba N. Syed
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2018-10-01
Saila:	Scientific Reports
Gaiak:	Fisetin Treatment Vemurafenib Melanoma Cultures Inhibit Melanoma Growth WM9 Melanoma Cells
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-018-33879-w
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