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Interleukin-18 and fibroblast growth factor 2 in combination is a useful diagnostic biomarker to distinguish adult-onset Still’s disease from sepsis

Abstract Objective To identify potential biomarkers to distinguish adult-onset Still’s disease (AOSD) from sepsis. Method We recruited 70 patients diagnosed with AOSD according to the Yamaguchi criteria, 22 patients with sepsis, and 118 age-matched controls. Serum levels of 40 cytokines were analyze...

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Principais autores: Tomohiro Koga, Remi Sumiyoshi, Kaori Furukawa, Shuntaro Sato, Kiyoshi Migita, Toshimasa Shimizu, Masataka Umeda, Yushiro Endo, Shoichi Fukui, Shin-ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Fumiaki Nonaka, Akihiro Yachie, Hideaki Kondo, Takahiro Maeda, Atsushi Kawakami
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-05-01
coleção:Arthritis Research & Therapy
Assuntos:
Adult-onset Still’s disease
Sepsis
IL-18
FGF-2
Cytokine profile
Acesso em linha:http://link.springer.com/article/10.1186/s13075-020-02200-4
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