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Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation

Protein arginylation by arginyl–transfer RNA protein transferase (ATE1) is emerging as a regulator protein function that is reminiscent of phosphorylation. For example, arginylation of β-actin has been found to regulate lamellipodial formation at the leading edge in fibroblasts. This finding suggest...

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Hlavní autoři: Lurong Lian, Aae Suzuki, Vincent Hayes, Sougata Saha, Xuemei Han, Tao Xu, John R Yates, Mortimer Poncz, Anna Kashina, Charles S. Abrams
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014-03-01
Edice:Haematologica
On-line přístup:https://haematologica.org/article/view/6974
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