<i>MAVS</i> Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4⁺ T Cell Infection in HIV-1-Infected Individuals

The mitochondrial antiviral protein MAVS is a key player in the induction of antiviral responses; however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the <i>MAVS</i> gene render MAVS insensitive to HIV-1-dependent...

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Bibliografiske detaljer

Principais autores:	Melissa Stunnenberg, Lisa van Pul, Joris K. Sprokholt, Karel A. van Dort, Sonja I. Gringhuis, Teunis B. H. Geijtenbeek, Neeltje A. Kootstra
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2020-07-01
Serier:	Viruses
Fag:	human immunodeficiency virus 1 viral sensing antiviral immunity <i>MAVS</i> genetic variation HIV-1 replication viral load
Online adgang:	https://www.mdpi.com/1999-4915/12/7/764
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