Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...

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Auteurs principaux:	Grazyna Adler, Izabela Uzar, Amina Valjevac, Emina Kiseljakovic, Emir Mahmutbegovic, Nermin N. Salkic, Mateusz A. Adler, Nevena Mahmutbegovic
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis Group 2022-05-01
Collection:	Annals of Human Biology
Sujets:	snps cytochrome p450 3a5 atp-binding cassette b1 pharmacogenetics
Accès en ligne:	http://dx.doi.org/10.1080/03014460.2022.2100477
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